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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9775e8f529595156eca491637881941204d163bbee6050356fd869eacb11938' 
  AND token = '9pKmxlV1e9flTvkrcuPrFG4GrnNGt+v0NCihZ2KvrQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}