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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab82db36d12e2dd130deb1e2c59228de404138335f185c53da89d499047c101' 
  AND token = 'gP+icbFcjekYLiVn7pzx8TfYoYVXX0KweV6+3IP2J+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}