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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85f175f44a2a51f33c76a7c0fe347e50b5fa8f7a1dac2a9594a1c3bcb101e60f' 
  AND token = '4V15OltrvHt4DtccxR+FASok+AIEBBaTegRWzsgYNYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}