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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efe7a29cc080bda7c2079140961093e3be05e4a02dbac6fe3ad147d009f285bd' 
  AND token = 'BSUGdNLrN0JfiU70X/sT6WbXfjKnLrrBkW9jGpGt+WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}