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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '236aed53a13d700de9c475bf7d6c1804d2f8a3a44f8bb3445c2deb89c2a9306f' 
  AND token = 'SzSpj7Jy/WsA089mK3RrF6plaUTrjg2kNkXfBakZpXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}