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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80259ebfc4c12904793e00bbe025f655e0f9f5480f240f7ca3167c55f009026' 
  AND token = 'YX58gYlpaFnGzJ2eU/LcbLgnrqRZoH9UTPToJpsZyZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}