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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51d0bd2542c67b9412a61cd76467586986ef5f81373b8622e58df61ec6dba80d' 
  AND token = 'q58UYqN+R6fDn3CtAYyrcR49TWNzeMpAvDf0rjsqwC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}