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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45163e447bd07c5610184c40e6cb793102ed68cea8538006722aec90d0c0145c' 
  AND token = 'l93dOxhxuPgoC2PymnFAnNfjbU8xLZ6rI0H0bgFePWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}