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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3f7c17c2141f40f266697355c3a6d48586bdbc4256232ecaaed9f019a6ad2e' 
  AND token = 'EL8OQMaA7yEyf1VlCVhEW7GDs8XiqAHyseYI3AaK8cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}