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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae016b804fe3e311717c129fdc72c9ea3365bae3f0cc81ddbb1def08d61ec4e3' 
  AND token = '3O5rnHR7PXf3Ki4IaGFKlwgn0fSd5bfSge9Hp46lV8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}