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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75226812b20ab2c9358e9be7baf0a3193f3ef9e759a0a52421ff73fa85598908' 
  AND token = 'P7iUCE4ScxmDt9iSW5n8klTY5o77Q+EKZAieVfF3gfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}