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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd981e6f92379e06bf8182e5a4a18923b802b6193718d3c6b9f0b272dd1d04a83' 
  AND token = '8/AR4l+6xqx08XF/k3JWlc6eVJbBrY47/nBnv3IBtHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}