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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb68c980eb81a27ee9aeb1ec855512040d2285603dcd924ae15c1b722abe6dcd' 
  AND token = 'jTe1Jb2der66d/+xUBMfeF4p+qM9xcS7G7+5omAnvD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}