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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5a8850c23e1f3aeee405ba96a1a711ee396557baf77aa5c5a95896d4cceeb61' 
  AND token = 'gcNYdLVwbNPb4v3Vr3s8CFWKKo2U8h7xlYAyjSCbVBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}