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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c9ad24131da3dd0a10616089d95c526368836af56c98114a56cdd98d179fd56' 
  AND token = 'O/sxdtIJsUR2EULX343wfA1ikiFWPnQiywt69xAEb38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}