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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9057db4413dfa56456701c3d13b77e86deb3af531ca5b54c9fdf541f883e1244' 
  AND token = 'UXGg8/Hmw651OE14zGyefBCJJDnc45yEX9xDXrwAxA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}