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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1cc7d1537a17b92e7cd4d7aca64e84243295926309c959943d65131946d641' 
  AND token = 'Akg9P9BS8VCAAozd6O1kpiTn/l5M+eVz82deZOVTYLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}