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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba43b688801a00670241a16dfe31f83469ad12db166196ca740b32e68cc44dcc' 
  AND token = 's2WUvpcZV/87ZEF8D54dd4NNWScyslIjDWRyq9Wxj6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}