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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81619e4f6592cc5a156a04bc5aa89bbd2145c515071eb34625d154a7f5922df5' 
  AND token = 'ng3bfa2TLIZDcGUtK0lW6RsYf8gI6Uv7AfiRguMobsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}