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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede8ae701d3c8e4498c4dceffd4144558a7d0229038bd49c6b91708d19593646' 
  AND token = 'kh91oRLyFk1kxDJ1fTmkdVjfvM7nFH6QTZ0peOPxgSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}