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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff1cb1252304b8d17f342c3e9e1fc55f5d2810e4c20e26f600d1044c6028dbb' 
  AND token = 'jkui00oYub8Bz5KMVDqeIOiJLWduTikrNU55DBiDfaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}