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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8764ec2a6cd69b8b3b01a6c9c89ff00b9f89fac71680a35258d981094157833' 
  AND token = 'LkUEy2YzO0mUj9mJ9ct77Nx8O6gmp/ZfY876OJIuKTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}