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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08087e86b4b80530d4970b56fcf6a0556c24c96bb9dc2286101a2c24898c1a4f' 
  AND token = 'HR4I3cX17ebvakU4xIcVfdojpVbAC2Yoxi0/Zmz7lBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}