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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd88805ab2b72b0427617bf4f6bd4e2c211d3544947aa87eb4b8b535c18b3d205' 
  AND token = 'dG0/AtFNoZJJvrtu/v5r3eCZau2Xvl38xbmS1jYA58Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}