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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a7a407bb713f9b8b93490b427eae48aafd6353f8a9f6fcbcd945f96c2f14d4' 
  AND token = 'PMtFoMT7OUQeC0uer6NGMK7LQh9RDfj7dIZxqEllvlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}