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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de698f6e861f1dd2be089e2202df6c20983fd8967735e9304a6bbdb6010eac2' 
  AND token = 'iE6QFMnn7nJVMMwWSgjQSlPQf5KNr1pqXef9IuyJ10A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}