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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c85d4f965976ebb3a0f5b5f326a482f772df512e99fe9b336927042d1e601316' 
  AND token = 'W0Td2SfxNmz9jAyGLHGMwjDLiBivXydtHvlmYFCp9F4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}