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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f73d3993a88eace7f468ffe4891b6c1146b299ad882dd6593a6f28993d6e86' 
  AND token = 'FbCoGJB68pjSi4uYc5CxsAjfFhCm7ZkplqzlxW04Y80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}