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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c94e544a906c7b9f62867b7bac8664c97555516ac0747d5ac4185516c1d49c' 
  AND token = 'JoAam6jZGExJ0DOAKK6YarDJzSt3WfgD8+siry6CZ/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}