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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef925eadc50383a0fea3d08c942f158ba8c16d510cfb85a84786d7d7e4f31b7a' 
  AND token = '5dB5bU/Hx/lcFG8d4YQiCDdX4R9siHVoJNPpvk1AGpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}