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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258286c29f41bc7491285ef16820135c259675f8906ffaee7361fd8d285562e3' 
  AND token = 'GPH4R6TYjEc1k1Xg9o6Xny/5/CeaQPFjVyq5LjY2iNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}