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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dfdf3b9256034b21052e925c64ce96d310cba3e813a48d870ef463bb2a86a86' 
  AND token = 'LP4ZmTsNH+mSOga11OsJH4uvuCmyNQGVei/fAbJrGnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}