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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '057c1a297e20ef686bbb986f846380348368afb34cb615d98df2115141c949fb' 
  AND token = 'HTtA3mhdwX1tmyCqM3MlKwNo0tfLb/Xq7PjL45QQuWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}