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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b9c0ed6ec39229f80124a61ce0c0c34db93422f33f8af120e141ada4ef49c10' 
  AND token = '4hDUDRwwaDNpUVomhUkr+AAE2DMf1PHum0oie5xtuns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}