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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e72cdd4b151a5c7541798af0d1b1d4a75b389770c183321d7aaec98c00efe6' 
  AND token = 'bszPKQ2/t/7w7ttbSZAWb/ZgizRhQpB5Hjvc6MiJftM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}