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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133afec941ff6b4b4d8099dfba5722e9475f15f70c54d85a3bc5a73b0e109d3e' 
  AND token = 'GkBs88SFGXi4Grhc90ZQKTGVrRYxRyIDTKoMyH7yKns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}