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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9107f57f7294768a15c1e5468f7e155bb9724f06fb4660c3d953ceaf0d6bbb43' 
  AND token = '+rC3/A8v4NO7171r1jADJ6DC4KicKt5IrWCfQ3yJvhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}