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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601a1fc880889c970f3ee616355f326df6f24fead7bbeaace44d2a41f63a5cb4' 
  AND token = 'KJTP2nxQHDSRBigmh0IP/MudMorQBSNl39t2wGngpmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}