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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be300c975f4a3f395fab1486e0aec8bde020c1ca6978014117afb2630fb3615' 
  AND token = 'G+wZwWgwsVf5L2zajdT3gEDWW8K62AITgCxcnb9O92k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}