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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '274a6ce2dad03f41b21825db129e1aaee72155bb550d8d109a3f99862eef9539' 
  AND token = 'ioCl+9iZ0o42kS9HPHb8CAtHc8pjX/fxXq6kE+GOeAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}