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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0edfea1513e8e1a5d81e082cd32fdd72ac566d62cb4e7e020683827d6f9dcbbf' 
  AND token = 'SwUrFyRU6rT/cWDGEcl4/BrugwXOFfBUQ1PNQfsdTv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}