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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8166532e155366d898f3cc552bc3b1d92b1f76ec2cb5c822b2bf8cd9aeb837' 
  AND token = '2PAhpcfxXbSHrF1JEZHsrfDHYO3LKlSBKQItzQxAJZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}