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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654f40e4d74eaf6412394df90f7dc9a0550091d991f90003bafaca600092f349' 
  AND token = 'DGGCqhQVwbSOK5rPQmLHKHISIc+WoIhHO4ipRUzPJ44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}