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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357daeeddc41a0492109256087f2ef5921822829800c8d5e84bdf60116f2cab8' 
  AND token = 'qDJEMsCJDxfZm5Of9lYs0J2eJYu8wslgce9Sve+OnBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}