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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4675973eb2b68dc1bad1df606f461547cfc6f95e191cc718b5ab7ea30c8784f2' 
  AND token = 'HIemthTUDywtjqCM0lox1lPBibF//zEQDRzWcRO2nQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}