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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7fa22be4526ab36c514e6bacbda60ab1bcaf72e23f248e2501c5eade2636ccf' 
  AND token = 'Lvi8FIlT3wzNC4oaqyofyKpmg9Xpd4WrgTWCEC12sBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}