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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ccc2efd850c21667c381c8c25198ec0f1372928eac430de99e7443a049c8fb1' 
  AND token = '9rAV761UXwRT/OOlyD6K+7faoB5wD/7yMNGggnLv0Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}