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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2374dca8f7b903425da31c705d1d36b5e3f22e41726ee8b532b38f1f6565004' 
  AND token = 'ZM5b4PnJ/tygwZggL0NSNMzonVzAxbfL56SaaYvakLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}