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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '625f494c817cdd779e1937dd93fdc2e5d109673dc821501825ac0c6cccd6cc05' 
  AND token = '6xeFlh/mp+d4/iVqPukK1j5p/aRNucmqIlN1BH5+QWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}