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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5517412dd8bf5a6ed745c31c51e2da1fb073e3b4092f2ddeb2488e2e87984df1' 
  AND token = 'jeH724fUMnpDiwhpP0VcBmmVh2TVeyIgRqMEHd5ABjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}